Fort Stockton is a regional center for government, medical care, and retail sales. Federal, state and regional offices located in Fort Stockton include the Texas A&M Cooperative Extension Service Region 6 Headquarters, the Texas Department of Public Safety, the United States Department of Agriculture, the Texas Workforce Commission and the United States Forestry Service.
The Pecos County Memorial Hospital and associated medical services provide care for large area of the Big Bend and Trans-Pecos region of Texas. A trade area that includes 10 counties and cities along the Mexican Border generates retail sales in the community. Counties in yellow are part of the Fort Stockton trade area. Trade area population is roughly 100,000.